Everything about megatomi.com
Everything about megatomi.com
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Our new Crystal clear+ tissue clearing procedure is the only real process that delipidates samples without alter in morphology and with minimal impact on structural integrity.
Megatome is usually a vibrating microtome built to section a broad number of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome allows significant-throughput tissue sectioning with uniform area profile, together with nominal tissue damage and knowledge reduction.
Antibodies could get months to diffuse as a result of only some millimeters of tissue, which has a steep labeling gradient from area to Main.
Megatome is suitable for precision: the blade vibrates at an increased frequency and bigger amplitude selection than other microtomes, and contains a exclusive deflection Management system.
SE employs a rotational electrical discipline to disperse very electromobile molecules (like antibodies or surfactant micelles) throughout a porous sample without harming electrically billed constructions inside the tissue. This enables two-four day clearing of intact organs,
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Megatome is a novel microtome which allows for prime-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimal tissue problems and data loss.
It’s time to enhance your microtome to Megatome. With correct superior-frequency slicing for an unmatched variety of sample sizes and kinds – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied applications.
Entirely delipidate whole mouse brains or comparably sized samples in only one working day with SmartBatch+, or in one 7 days with our passive clearing kit.
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SHIELD avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, protecting specimens for several rounds of processing.
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Our novel Defend tissue preservation procedure sorts intramolecular bonds using polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.